Cardiac Output and other Haemodynamic Parameters. All in 20 seconds! Non Invasively. Accurately.

NICaS | Clinical Applications | CRT Optimisation, UK

CRT Optimization - Current Status


  • The theory behind CRT optimization is that CRT can be programmed specifically to meet the needs of an individual patient in such a way that a non-responder or suboptimal responder will derive more benefit from CRT
  • This is done by optimizing AV and VV delay so that Aortic Velocity Time Integral (VTI) measured by Echo Doppler is maximized (VTI is correlated to Cardiac Output)
  • Due to high cost and complexity of Echo Doppler measurement, CRT optimization is rarely carried out
  • This results in a compromised treatment, high non responder rate and a reduced quality of life and life expectancy for CRT implanted patients


CRT Optimization Suggested by NICaSTM Cardiac Output


  • NICaSTM is a revolutionary device that is capable of providing a continuous Cardiac Output reading enabling a simple and cost effective CRT optimization
  • This enables an improved responder rate and an increased quality of life and life expectancy for CRT implanted patients 
  • NICaSTM converts changes in arterial electrical resistance to changes in blood volume by attaching two sensors to the patient’s wrist and opposite ankle, without requiring the patient to undress 
  • NICaSTM  can provide direct changes in CO without the need to measure correlated parameters such as Echo Doppler VTI


Figure 1. Comparative Measurement Screen

CRT Figure 1


Related Clinical Studies:


Europace 99 CO Based Vs Empirically AV Interval

ICG Taskforce Austria Impedance cardiography: a useful and reliable tool in optimization of cardiac resynchronization devices

Europace 2008 Barold Iii88 95 Echocardiographic optimization of the atrioventricular and interventricular intervals during cardiac resynchronization

CRT Optimization By Using Nicas


Non Invasive. Accurate. Revolutionary. LEARN MORE


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